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DEVELOPMENT OF NOVEL ALUMINA BY SOLID-STATE REACTION FOR 99MO/99MTC ADSORBENT MATERIAL

Munir, Miftakhul and Lestari, Enny and Hambali, Hambali and Kadarisman, Kadarisman and Marlina, Marlina (2019) DEVELOPMENT OF NOVEL ALUMINA BY SOLID-STATE REACTION FOR 99MO/99MTC ADSORBENT MATERIAL. Jurnal Al Kimia, 7 (2). ISSN 2549-9335

[img] Text (Technetium-99m (99mTc), a daughter radionuclide of molybdenum-99 (99Mo), is the most widely used radiodiagnostic agent due to its ideal characteristics.)
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Abstract

Technetium-99m (99mTc), a daughter radionuclide of molybdenum-99 (99Mo), is the most widely used radiodiagnostic agent due to its ideal characteristics. The separation of this radionuclide from 99Mo is commonly performed using alumina. However, a new production method of this radionuclide, which employs a low specific activity 99Mo, makes alumina no longer suitable as separation material. This study aims to develop novel alumina using a facile solid-state reaction for 99Mo/99mTc generator system. The SS-alumina was synthesized from aluminium nitrate nonahydrate and ammonium bicarbonate without solvent. The resulted SS-alumina was then analyzed by FTIR and BET method. 99Mo adsorption and 99mTc releasing study on a series of pH were also performed. FTIR study revealed that the resulting material was Al2O3 with a surface area of 237.65 m2/g. The adsorption capacity, 99mTc yield, 99Mo breakthrough, and alumina breakthrough were 76.06 mg Mo/g alumina, 80.31%, 56.5 µCi/mCi 99mTc, and less than 5 mg/mL, respectively. The elution profile shows a high activity of 99mTc in 2nd and 3rd fraction. It is concluded that the SS-alumina shows good performance as adsorbent material for separation of a 99Mo/99mTc and further work is now underway.

Item Type: Article
Subjects: Isotop dan Radiasi > Produksi Isotop dan Sumber Radiasi > Teknik Produksi Radioisotop
Divisions: Pusat Teknologi Radioisotop dan Radiofarmaka
Depositing User: USER PTRR BATAN
Date Deposited: 02 Jul 2021 03:14
Last Modified: 02 Jul 2021 03:14
URI: http://repo-nkm.batan.go.id/id/eprint/10356

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