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Automated Measurement of Haemozoin (Malarial Pigment) Area in Liver Histology Using Image J 1.6

Dwi, Ramadhani and Tur, Rahardjo and Siti, Nurhayati (2012) Automated Measurement of Haemozoin (Malarial Pigment) Area in Liver Histology Using Image J 1.6. Prosiding The 6th – Electrical Power, Electronics, Communications, and Informatics International Seminar 2012. B21-B24.


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Common histopathological changes in the liver due to Plasmodium infection is the presence of haemozoin (malarial pigment) in liver histology section. Identification of haemozoin generally done manually under microscope. Measurement of haemozoin area rarely done because it is quite difficult to separate the haemozoin area from other element in liver histology. Identification and measurement haemozoin area can be done by image analysis using ImageJ. ImageJ is a public domain Java image processing program that enables a plugin development. Plugins are small Java modules for extending the functionality of ImageJ by using a simple standardized interface. Aim of this research is developed ImageJ plugin to measure the haemozoin area in liver histology. Totally 60 random liver histology images were analyzed using our plugin. Algorithm of plugin contain several sequential stages, such as splitting channels, thresholding the image for detection haemozoin area in blue channel and measure haemozoin area. Average haemozoin area from 60 images defined with our plugin was 3884.5 µm2 . Our plugin succeeded in detecting and measuring the haemozoin area in liver images at approximately 3.91 seconds.

Item Type: Article
Subjects: Isotop dan Radiasi > Pemanfaatan Isotop dan Radiasi
Divisions: Pusat Teknologi Keselamatan dan Metrologi Radiasi
Depositing User: USER PTKMR BATAN
Date Deposited: 03 Jul 2018 01:17
Last Modified: 03 Jul 2018 01:17
URI: http://repo-nkm.batan.go.id/id/eprint/3162

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