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Automated Detection of Congested Central Vein Liver Histology of Mice Infected with Plasmodium berghei Using CellProfiler 2.0

Tur, Rahardjo and Dwi, Ramadhani and Siti, Nurhayati (2012) Automated Detection of Congested Central Vein Liver Histology of Mice Infected with Plasmodium berghei Using CellProfiler 2.0. Prosiding The 6th – Electrical Power, Electronics, Communications, and Informatics International Seminar 2012. pp. 1-3.

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Abstract

Malaria is initiated by Plasmodium sporozoites infections, which are inoculated by mosquitoes. Histopathologic lesions often described in the liver of rodent with malaria are congested central vein with neutrophils and eusinophils within the lumen. Detection of congested central vein has a possibility to do automatically using image analysis software. Here the used of CellProfiler an open access cell image analysis software for automated detection congested central vein liver histology of mice infected with Plasmodium berghei is reported. The results are compared to the manual detection. Wilcoxon rank test was used for statistical analysis with H0 hypothesis that means there was no significant difference between manual analysis and those with CellProfiler. Totally 10 images were analysed for both manually and using CellProfiler. Results showed that there were no significant difference between manual and automatic counting (p>0,05). Overall it appears that in our research analyzes with CellProfiler are comparable but not better than manual.

Item Type: Article
Subjects: Isotop dan Radiasi > Pemanfaatan Isotop dan Radiasi > Bidang Kesehatan
Isotop dan Radiasi > Pemanfaatan Isotop dan Radiasi
Divisions: Pusat Teknologi Keselamatan dan Metrologi Radiasi
Depositing User: USER PTKMR BATAN
Date Deposited: 03 Jul 2018 01:21
Last Modified: 03 Jul 2018 01:21
URI: http://repo-nkm.batan.go.id/id/eprint/3255

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